Institut für Anatomie und Zellbiologie

    Publikationen 2023

    Rajendran R, Rajendran V, Böttiger G, Stadelmann C, Shirvanchi K, von Au L, Bhushan S, Wallendszus N, Schunin D, Westbrock V, Liebisch G, Ergün S, Karnati S, Berghoff M
    The small molecule fibroblast growth factor receptor inhibitor infigratinib exerts anti-inflammatory effects and remyelination in a model of multiple sclerosis
    Br J Pharmacol. 2023 Dec;180(23):2989-3007. doi: 10.1111/bph.16186. Epub 2023 Jul 31. PMID: 37400950

    Hartung V, Gruschwitz P, Huflage H, Augustin AM, Kleefeldt F, Peter D, Lichthardt S, Ergün S, Bley TA, Grunz JP, Petritsch B
    Photon-Counting Detector CT for Femoral Stent Imaging in an Extracorporeally Perfused Human Cadaveric Model
    Invest Radiol. 2023 Oct 9. doi: 10.1097/RLI.0000000000001019. Online ahead of print. PMID: 37812470

    Conrads N, Kunz AS, Huflage H, Patzer TS, Luetkens KS, Ergün S, Herbst M, Herold S, Weber T, Bley TA, Grunz JP
    Upright Tomosynthesis of the Lumbar Spine
    Acad Radiol. 2023 Sep 18:S1076-6332(23)00457-9. doi: 10.1016/j.acra.2023.08.036. Online ahead of print. PMID: 37730493

    Patzer TS, Kunz AS, Huflage H, Luetkens KS, Conrads N, Pannenbecker P, Jakuscheit A, Reppenhagen S, Ergün S, Bley TA, Grunz JP
    Rotational alignment of the lower extremity in the presence of total knee endoprosthesis: Reproducibility of torsion analyses using ultra-low-dose photon-counting CT
    Eur J Radiol. 2023 Aug 19;167:111055. doi: 10.1016/j.ejrad.2023.111055. Online ahead of print. PMID: 37632998

    Kunke M, Knöfler H, Dahlke E, Zanon Rodriguez L, Böttner M, Larionov A, Saudenova M, Ohrenschall GM, Westermann M, Porubsky S, Bernardes JP, Häsler R, Magnin JL, Koepsell H, Jouret F, Theilig F
    Targeted deletion of von-Hippel-Lindau in the proximal tubule conditions the kidney against early diabetic kidney disease
    Cell Death Dis. 2023 Aug 26;14(8):562. doi: 10.1038/s41419-023-06074-7. PMID: 37626062

    Madrahimov N, Mutsenko V, Natanov R, Radaković D, Klapproth A, Hassan M, Rosenfeldt M, Kleefeldt F, Aleksic I, Ergün S, Otto C, Leyh RG, Bening C
    Multiorgan recovery in a cadaver body using mild hypothermic ECMO treatment in a murine model
    Intensive Care Med Exp. 2023 Aug 4;11(1):46. doi: 10.1186/s40635-023-00534-2. PMID: 37537415

    Huflage H, Hendel R, Kunz AS, Ergün S, Afat S, Petri N, Hartung V, Gruschwitz P, Bley TA, Grunz JP
    Investigating the Small Pixel Effect in Ultra-High Resolution Photon-Counting CT of the Lung
    Invest Radiol. 2023 Aug 9. doi: 10.1097/RLI.0000000000001013. Online ahead of print. PMID: 37552040

    Elsner C, Kunz AS, Wagner N, Huflage H, Hübner S, Luetkens KS, Bley TA, Schmitt R,
    Ergün S, Grunz JP

    MRI-Based Evaluation of the Flexor Digitorum Superficialis Anatomy: Investigating the Prevalence and Morphometry of the "Chiasma Antebrachii"
    Diagnostics (Basel). 2023 Jul 19;13(14):2406. doi: 10.3390/diagnostics13142406. PMID: 37510150

    Gruschwitz P, Hartung V, Kleefeldt F, Ergün S, Lichthardt S, Huflage H, Hendel R, Kunz AS, Pannenbecker P, Kuhl PJ, Augustin AM, Bley TA, Petritsch B, Grunz JP
    Standardized assessment of vascular reconstruction kernels in photon-counting CT angiographies of the leg using a continuous extracorporeal perfusion model
    Sci Rep. 2023 Jul 26;13(1):12109. doi: 10.1038/s41598-023-39063-z. PMID: 37495759

    Rajendran R, Rajendran V, Böttiger G, Stadelmann C, Shirvanchi K, von Au L, Bhushan S, Wallendszus N, Schunin D, Westbrock V, Liebisch G, Ergün S, Karnati S, Berghoff M
    The small molecule FGFR inhibitor infigratinib exerts anti-inflammatory effects and remyelination in a model of multiple sclerosis
    Br J Pharmacol. 2023 Jul 3. doi: 10.1111/bph.16186. Online ahead of print. PMID: 37400950

    Feldle P, Grunz JP, Kunz AS, Patzer TS, Huflage H, Hendel R, Luetkens KS, Ergün S, Bley TA, Conrads N
    Weight-bearing gantry-free cone-beam CT of the lumbar spine: Image quality analysis and dose efficiency
    Eur J Radiol. 2023 Jun 25;165:110951. doi: 10.1016/j.ejrad.2023.110951. Online ahead of print. PMID: 37379623

    Luetkens KS, Grunz JP, Kunz AS, Huflage H, Weißenberger M, Hartung V, Patzer TS, Gruschwitz P, Ergün S, Bley TA, Feldle P
    Ultra-High-Resolution Photon-Counting Detector CT Arthrography of the Ankle: A Feasibility Study
    Diagnostics (Basel). 2023 Jun 28;13(13):2201. doi: 10.3390/diagnostics13132201. PMID: 37443595

    Patzer TS, Kunz AS, Huflage H, Luetkens KS, Conrads N, Gruschwitz P, Pannenbecker P, Ergün S, Bley TA, Grunz JP
    Quantitative and qualitative image quality assessment in shoulder examinations with a first-generation photon-counting detector CT
    Sci Rep. 2023 May 22;13(1):8226. doi: 10.1038/s41598-023-35367-2. PMID: 37217553

    Bohley M, Dillinger AE, Braunger BM, Tamm ER, Goepferich A
    Intravenous injection of cyclosporin A loaded lipid nanocapsules fights inflammation and immune system activation in a mouse model of diabetic retinopathy
    Drug Deliv Transl Res. 2023 May 19. doi: 10.1007/s13346-023-01350-7. Online ahead of print. PMID: 37208562

    Gruschwitz P, Hartung V, Kleefeldt F, Peter D, Lichthardt S, Huflage H, Grunz JP, Augustin AM, Ergün S, Bley TA, Petritsch B
    Continuous extracorporeal femoral perfusion model for intravascular ultrasound, computed tomography and digital subtraction angiography
    PLoS One. 2023 May 23;18(5):e0285810. doi: 10.1371/journal.pone.0285810. eCollection 2023. PMID: 37220113

    Patzer TS, Kunz AS, Huflage H, Conrads N, Luetkens KS, Pannenbecker P, Paul MM, Ergün S, Bley TA, Grunz JP
    Ultrahigh-Resolution Photon-Counting CT in Cadaveric Fracture Models: Spatial Frequency Is Not Everything
    Diagnostics (Basel). 2023 May 9;13(10):1677. doi: 10.3390/diagnostics13101677. PMID: 37238160

    Braunger BM, Gießl A, Schlötzer-Schrehardt U
    The Blood-ocular Barriers and their Dysfunction: Anatomy, Physiology, Pathology
    Klin Monbl Augenheilkd. 2023 May;240(5):650-661. doi: 10.1055/a-2063-8957. Epub 2023 May 19. PMID: 37207638

    Gruschwitz P, Hartung V, Kleefeldt F, Ergün S, Huflage H, Peter D, Hendel R, Patzer TS, Pannenbecker P, Kuhl PJ, Bley TA, Petritsch B, Grunz JP
    Photon-Counting Versus Energy-Integrating Detector CT Angiography of the Lower Extremity in a Human Cadaveric Model With Continuous Extracorporeal Perfusion
    Invest Radiol. 2023 Apr 24. doi: 10.1097/RLI.0000000000000982. Online ahead of print. PMID: 37185253

    Gredic M, Karnati S, Ruppert C, Guenther A, Avdeev SN, Kosanovic D
    Combined Pulmonary Fibrosis and Emphysema: When Scylla and Charybdis Ally
    Cells 2023, 12(9), 1278; Published: 28 April 2023

    Rockel AF, Wagner N, Spenger P, Ergün S, Wörsdörfer P
    Neuro-mesodermal assembloids recapitulate aspects of peripheral nervous system development in vitro
    Stem Cell Reports. 2023 Apr 6:S2213-6711(23)00100-5. doi: 10.1016/j.stemcr.2023.03.012. Online ahead of print. PMID: 37084722

    Behera A, Biswas M, Ergün S, Karnati S, Sonawane A
    Detection of Peroxisomal Proteins During Mycobacterial Infection
    Methods Mol Biol. 2023;2643:123-134. doi: 10.1007/978-1-0716-3048-8_9. PMID: 36952182

    Klein T, Sauer M, Ergün S, Karnati S
    Direct Stochastic Optical Reconstruction Microscopy (dSTORM) of Peroxisomes
    Methods Mol Biol. 2023;2643:85-92. doi: 10.1007/978-1-0716-3048-8_6. PMID: 36952179

    Ascheid D, Baumann M, Funke C, Volz J, Pinnecker J, Friedrich M, Höhn M, Nandigama R, Ergün S, Nieswandt B, Heinze KG, Henke E
    Image-based modeling of vascular organization to evaluate anti-angiogenic therapy
    Biol Direct. 2023 Mar 15;18(1):10. doi: 10.1186/s13062-023-00365-x. PMID: 36922848

    Indari O, Ergün S, Karnati S, Jha HCh
    Herpesviral interplay with peroxisome: An underexplored viral nich
    Genes Dis. 2023 Mar 24;10(4):1133-1135. doi: 10.1016/j.gendis.2023.01.033. eCollection 2023 Jul. PMID: 37397512

    Oruqaj G, Karnati S, Kanth Kotarkonda L, Boateng E , Bartkuhn M , Zhang W , Ruppert C  , Günther A  , Bartholin L , Shi W  , Baumgart-Vogt E
    Transforming Growth Factor-β1 Regulates Peroxisomal Genes/Proteins via Smad Signaling in Idiopathic Pulmonary Fibrosis Fibroblasts and Transgenic Mouse Models
    PMID: 36521562, DOI: 10.1016/j.ajpath.2022.11.006

    Watermann C,  Meyer MT,  Wagner S,  Wittekindt C,  Klussmann JP, Erguen S, Baumgart-Vogt E, Karnati S
    Peroxisomes Are Highly Abundant and Heterogeneous in Human Parotid Glands
    Int. J. Mol. Sci. 2023, 24(5), 4783;

    Huflage H, Grunz JP, Patzer TS, Pannenbecker P, Feldle P, Sauer ST, Petritsch B, Ergün S, Bley TA, Kunz AS
    Potential of Unenhanced Ultra-Low-Dose Abdominal Photon-Counting CT with Tin Filtration: A Cadaveric Study
    Diagnostics (Basel). 2023 Feb 7;13(4):603. doi: 10.3390/diagnostics13040603. PMID: 368320

    Wihadmadyatami H, Karnati S, Ergün S, Kustiati U, Tirtosari DR, Kusindarta DL, Tjahjono Y
    Ocimum sanctum Linn. Ethanolic extract promotes an antiproliferative and apoptosis activity in MCF-7 and T47D breast cancer cell lines mediated by upregulation of ROS/RNS, Caspase 9, and Caspase 3: an in silico and in vitro study
    published: 06 Feb 2023, 12:136

    Keller T, Trinks N, Brand J, Trippmacher S, Stahlhut P, Albrecht K, Papastavrou G, Koepsell H, Sauer M, Groll J
    Design of Nanohydrogels for Targeted Intracellular Drug Transport to the Trans-Golgi Network
    Adv Healthc Mater. 2023 Feb 4:e2201794. doi: 10.1002/adhm.202201794. Online ahead of print. PMID: 36739269

    Conrads N, Grunz JP, Huflage H, Luetkens KS, Feldle P, Pennig L, Ergün S, Alexander Bley T, Petritsch B, Kunz AS
    Ultrahigh-resolution computed tomography of the cervical spine without dose penalty employing a cadmium-telluride photon-counting detector
    Eur J Radiol. 2023 Jan 27;160:110718. doi: 10.1016/j.ejrad.2023.110718. Online ahead of print. PMID: 36731400

    Ergün S, Ghoreishi Y, Hübner S, Grunz JP, Huflage H, Bley TA, Wagner N, Naumann M
    Old name, new face: a systematic analysis of flexor digitorum superficialis muscle with "chiasma antebrachii"
    Ann Anat. 2023 Jan 20:152052. doi: 10.1016/j.aanat.2023.152052. Online ahead of print. PMID: 36690043

    Chen R, Buchmann S, Kroth A, Arias-Loza AP, Kohlhaas M, Wagner N, Grüner G, Nickel A, Cirnu A, Williams T, Maack C, Ergün S, Frantz S, Gerull B
    Mechanistic Insights of the LEMD2 p.L13R Mutation and Its Role in Cardiomyopathy
    Circ Res. 2023 Jan 20;132(2):e43-e58. doi: 10.1161/CIRCRESAHA.122.321929. Epub 2023 Jan 4. PMID: 36656972

    Zubiaga L, Briand O, Auger F, Touche V, Hubert T, Thevenet J, Marciniak C, Quenon A, Bonner C, Peschard S, Raverdy V, Daoudi M, Kerr-Conte J, Pasquetti G, Koepsell H, Zdzieblo D, Mühlemann M, Thorens B, Delzenne ND, Bindels LB, Deprez B, Vantyghem MC, Laferrère B, Staels B, Huglo D, Lestavel S, Pattou F
    Oral metformin transiently lowers post-prandial glucose response by reducing the apical expression of sodium-glucose co-transporter 1 in enterocytes
    iScience. 2023 Jan 25;26(4):106057. doi: 10.1016/j.isci.2023.106057. eCollection 2023 Apr 21. PMID: 36942050

    Elsner C  , Ergün S , Wagner N
    Biogenesis and release of endothelial extracellular vesicles: Morphological aspects
    Affiliations PMID: 36183939, DOI: 10.1016/j.aanat.2022.152006

    Indari O, Rani A, Baral B, Ergün S, Bala K, Karnati S, Jha HC
    Modulation of peroxisomal compartment by Epstein-Barr virus
    Microb Pathog. 2022 Dec 13;174:105946. doi: 10.1016/j.micpath.2022.105946. Online ahead of print. PMID: 36526038