Intern
    Institut für Anatomie und Zellbiologie

    Publikationen 2022

    Tjahjono Y,Caroline Foe K, Karnati S, Ergün S, Esar SY, Wijaya H, Hadinugroho W, Wihadmadyatami H, Kusindart DL
    Synthesis, Characterization, and Application of 2-((3-(Chloromethyl)-benzoyl)oxy)benzoic Acid: A Review
    ACS Omega 2022, Publication Date:December 28, 2022, doi.org/10.1021/acsomega.2c05566

    Jordan MC, Bröer D, Fischer C, Heilig P, Gilbert F, Hölscher-Doht S, Kalogirou C, Popp K, Grunz JP, Huflage H, Jakubietz RG, Ergün S, Meffert RH
    Development and preclinical evaluation of a cable-clamp fixation device for a disrupted pubic symphysis
    Commun Med (Lond). 2022 Dec 22;2(1):164. doi: 10.1038/s43856-022-00227-z. PMID: 36550296

    Oruqaj G, Karnati S, Kotarkonda L, Boateng E, Bartkuhn M, Zhang W, Ruppert C, Günther A, Bartholin L, Shi W, Baumgart-Vogt E
    TGF-β1 Regulates Peroxisomal Genes/Proteins via Smad Signaling in Idiopathic Pulmonary Fibrosis Fibroblasts and Transgenic Mouse Models
    https://doi.org/10.1016/j.ajpath.2022.11.006

    Kustiati U, Ergün S,  Karnati S, Nugrahaningsih D,  Kusindarta DL, Wihadmadyatami H
    Ethanolischer Extrakt ausOcimum sanctumLinn. Hemmt die Zellmigration menschlicher Lungen-Adenokarzinomzellen (A549) durch Herunterregulierung von Integrin αvβ3, α5β1 und VEGF
    Sci. Pharm. 2022,90(4), 69; https://doi.org/10.3390/scipharm90040069

    Rajendran R, Rajendran V, Gupta L, Shirvanchi K, Schunin D, Karnati S, Giraldo-Velásquez M, Berghoff M
    Interferon Beta-1a versus Combined Interferon Beta-1a and Oligodendrocyte-Specific FGFR1 Deletion in Experimental Autoimmune Encephalomyelitis
    Int J Mol Sci. 2022 Oct 12;23(20):12183. doi: 10.3390/ijms232012183. PMID: 36293040

    Huflage H, Grunz JP, Kunz AS, Patzer TS, Sauer ST, Christner SA, Petritsch B, Ergün S, Bley TA, Luetkens KS
    Potential of employing a quantum iterative reconstruction algorithm for ultra-high-resolution photon-counting detector CT of the hip
    Radiography (Lond). 2022 Oct 20;29(1):44-49. doi: 10.1016/j.radi.2022.09.010. Online ahead of print. PMID: 36274316

    Elsner C, Ergün S , Wagner N
    Biogenesis and release of endothelial extracellular vesicles: Morphological aspects
    Ann Anat. 2022 Sep 29;245:152006. doi: 10.1016/j.aanat.2022.152006. Online ahead of print. PMID: 36183939

    Kunz AS, Patzer TS, Grunz JP, Luetkens KS, Hartung V, Hendel R, Fieber T, Genest F, Ergün S, Bley TA, Huflage H
    Metal artifact reduction in ultra-high-resolution cone-beam CT imaging with a twin robotic X-ray system
    Sci Rep. 2022 Sep 16;12(1):15549. doi: 10.1038/s41598-022-19978-9. PMID: 36114270

    Reschke M, Salvador E, Schlegel N, Burek M, Karnati S, Wunder C, Förster CY
    Isosteviol Sodium (STVNA) Reduces Pro-Inflammatory Cytokine IL-6 and GM-CSF in an In Vitro Murine Stroke Model of the Blood-Brain Barrier (BBB)
    Pharmaceutics. 2022 Aug 23;14(9):1753. doi: 10.3390/pharmaceutics14091753. PMID: 36145501

    Shityakov S, Nagai M, Ergün S, Braunger BM, Förster CY
    The Protective Effects of Neurotrophins and MicroRNA in Diabetic Retinopathy, Nephropathy and Heart Failure via Regulating Endothelial Function
    Biomolecules. 2022 Aug 12;12(8):1113. doi: 10.3390/biom12081113. PMID: 36009007

    Luetkens KS, Grunz JP, Paul MM, Huflage H, Conrads N, Patzer TS, Gruschwitz P, Ergün S, Bley TA, Kunz AS
    One-stop-shop CT arthrography of the wrist without subject repositioning by means of gantry-free cone-beam CT
    Sci Rep. 2022 Aug 24;12(1):14422. doi: 10.1038/s41598-022-18395-2. PMID: 36002544

    IF Kusuma, U Damia, EI Megawati, FCE Saputra, S Karnati, DL Kusindarta, H Wihadmadyatami
    Morphology of lingual papillae in the Javan mongoose (Herpestes javanicus) by scanning electron microscopy and light microscopy
    First published: 20 August 2022 https://doi.org/10.1111/ahe.12848

    Feldheim J, Wend D, Lauer MJ, Monoranu CM, Glas M, Kleinschnitz C, Ernestus RI, Braunger BM, Meybohm P, Hagemann C, Burek M
    Protocadherin Gamma C3 (PCDHGC3) Is Strongly Expressed in Glioblastoma and Its High Expression Is Associated with Longer Progression-Free Survival of Patients
    Int J Mol Sci. 2022 Jul 22;23(15):8101. doi: 10.3390/ijms23158101. PMID: 35897674

    Grunz JP, Heidenreich JF, Lennartz S, Weighardt JP, Bley TA, Ergün S, Petritsch B, Huflage H
    Spectral Shaping Via Tin Prefiltration in Ultra-High-Resolution Photon-Counting and Energy-Integrating Detector CT of the Temporal Bone
    Invest Radiol. 2022 Jun 24. doi: 10.1097/RLI.0000000000000901. Online ahead of print. PMID: 35776435

    Keller T, Koepsell H, Groll J
    Evaluation of the Influence of Biosurface Design on the Interaction between the Regulatory Peptide RS1-reg and ODC1 Reveals a Membrane-Dependent Affinity Increase
    Adv Biol (Weinh). 2022 Jun 23:e2101108. doi: 10.1002/adbi.202101108. Online ahead of print. PMID: 35735188

    Huflage H, Grunz JP, Hackenbroch C, Halt D, Luetkens KS, Alfred Schmidt AM, Patzer TS, Ergün S, Bley TA, Kunz AS
    Metal artefact reduction in low-dose computed tomography: Benefits of tin prefiltration versus postprocessing of dual-energy datasets over conventional CT imaging
    Radiography (Lond). 2022 Jun 18;28(3):690-696. doi: 10.1016/j.radi.2022.05.006. Online ahead of print. PMID: 35728278

    Grunz JP, Petritsch B, Luetkens KS, Kunz AS, Lennartz S, Ergün S, Bley TA, Huflage H
    Ultra-Low-Dose Photon-Counting CT Imaging of the Paranasal Sinus With Tin Prefiltration: How Low Can We Go?
    Invest Radiol. 2022 May 6. doi: 10.1097/RLI.0000000000000887. Online ahead of print. PMID: 35703452

    Laich Y, Wolf J, Hajdu RI, Schlecht A, Bucher F, Pauleikhoff L, Busch M, Martin G, Faatz H, Killmer S, Bengsch B, Stahl A, Lommatzsch A, Schlunck G, Agostini H, Boneva S, Lange C
    Single-Cell Protein and Transcriptional Characterization of Epiretinal Membranes From Patients With Proliferative Vitreoretinopathy
    Invest Ophthalmol Vis Sci. 2022 May 2;63(5):17. doi: 10.1167/iovs.63.5.17. PMID: 35579905

    Bachhuka A, Yadav TC, Santos A, Marsal L, Ergün S, Karnati S
    Neue Nanomaterialien für Peroxisomen
    Materialstoday Advances, August 2022, 100265, https://doi.org/10.1016/j.mtadv.2022.100265

    Ergün S, Wörsdörfer P
    Organoids, Assembloids and Embryoids: New Avenues for Developmental Biology, Disease Modeling, Drug Testing and Toxicity Assessment without Animal Experimentation
    Organoids 2022, 1(1), 37-40; https://doi.org/10.3390/organoids1010004, Received: 12 April 2022 / Accepted: 14 April 2022 / Published: 22 April 2022

    Schmidt S  , Alt Y, Deoghare N,  Krüger S, Kern A, Rockel AF, Wagner N, Ergün S, Wörsdörfer P
    A Blood Vessel Organoid Model Recapitulating Aspects of Vasculogenesis, Angiogenesis and Vessel Wall Maturation
    Organoids 2022, 1(1), 41-53; https://doi.org/10.3390/organoids1010005, Received: 28 March 2022 / Revised: 14 April 2022 / Accepted: 26 April 2022 / Published: 28 April 2022

    Eckenstaler R, Ripperger A, Hauke M, Braun H, Ergün S, Schwedhelm E, Benndorf RA
    Thromboxane A2 receptor activation via Gα13-RhoA/C-ROCK-LIMK2-dependent signal transduction inhibits angiogenic sprouting of human endothelial cells
    Biochem Pharmacol. 2022 May 4:115069. doi: 10.1016/j.bcp.2022.115069. Online ahead of print. PMID: 35525325

    Luetkens KS, Huflage H, Kunz AS, Ritschl L, Herbst M, Kappler S, Ergün S, Goertz L, Pennig L, Bley TA, Gassenmaier T, Grunz JP
    The effect of tin prefiltration on extremity cone-beam CT imaging with a twin robotic X-ray system
    Radiography (Lond). 2022 May;28(2):433-439. doi: 10.1016/j.radi.2021.10.009. Epub 2021 Oct 27. PMID: 34716089

    Gergs U, Jahn T, Schulz N, Großmann C, Rueckschloss U, Demus U, Buchwalow IB, Neumann J
    Protein Phosphatase 2A Improves Cardiac Functional Response to Ischemia and Sepsis
    Int J Mol Sci. 2022 Apr 23;23(9):4688. doi: 10.3390/ijms23094688. PMID: 35563079

    Karnati S, Guntas G, Rajendran R, Shityakov S, Höring M, Liebisch G, Kosanovic D, Ergün S, Nagai M, Förster CY
    Quantitative Lipidomic Analysis of Takotsubo Syndrome Patients' Serum
    Front Cardiovasc Med. 2022 Apr 19;9:797154. doi: 10.3389/fcvm.2022.797154. eCollection 2022. PMID: 35514439

    Wang H, Srikanth Karnati S,  Madhusudhan T
    Regulation of the Homeostatic Unfolded Protein Response in Diabetic Nephropathy
    Pharmaceuticals (Basel). 2022 Mar 25;15(4):401. doi: 10.3390/ph15040401. PMID: 35455399

    Schlecht A, Wolf J, Boneva S, Prinz G, Braunger BM, Wieghofer P, Agostini H, Schlunck G, Lange C
    Transcriptional and Distributional Profiling of Microglia in Retinal Angiomatous Proliferation
    PMID: 35408803 2022 Mar 22;23(7):3443. doi: 10.3390/ijms23073443

    Zhang J, Cai J, Cui Y, Jiang S, Wei J, Kim YC, Chan J, Thalakola A, Le T, Xu L, Wang L, Jiang K, Wang X, Wang H, Cheng F, Buggs J, Koepsell H, Vallon V, Liu R
    Role of the macula densa sodium glucose cotransporter type 1-neuronal nitric oxide synthase-tubuloglomerular feedback pathway in diabetic hyperfiltration
    Kidney Int. 2022 Mar;101(3):541-550. doi: 10.1016/j.kint.2021.10.037. Epub 2021 Nov 26. PMID: 34843754

    Bielmeier CB, Schmitt S, Kleefeldt N , Boneva SK , Schlecht A, Vallon M, Tamm ER, Hillenkamp J, Ergün S , Neueder A,  Braunger B
    Deficiency in Retinal TGFβ Signaling Aggravates Neurodegeneration by Modulating Pro-Apoptotic and MAP Kinase Pathways
    Int J Mol Sci. 2022 Feb 27;23(5):2626. doi: 10.3390/ijms23052626

    Kleefeldt F, Upcin B, Bömmel H, Schulz C, Eckner G, Allmanritter J, Bauer J, Braunger B, Rueckschloss U, Ergün S
    Bone marrow-independent adventitial macrophage progenitor cells contribute to angiogenesis
    Cell Death Dis. 2022 Mar 9;13(3):220. doi: 10.1038/s41419-022-04605-2. PMID: 35264563

    Eckenstaler R , Ripperger A, Hauke M, Petermann M, Hemkemeyer S, Schwedhelm E, Ergün S, Frye M, Werz O, Koeberle A, Braun H, Benndorf RA Thromboxane A 2 Receptor-Driven COX-2-Dependent Feedback Loop That Affects Endothelial Homeostasis and Angiogenesis
    Arterioscler Thromb Vasc Biol. 2022 Mar 3; ATVBAHA121317380. doi: 10.1161/ATVBAHA.121.317380

    Wolf J, Boneva S, Schlecht A, Lapp T, Auw-Haedrich C, Lagrèze W, Agostini H, Reinhard T, Schlunck G, Lange C
    The Human Eye Transcriptome Atlas: A searchable comparative transcriptome database for healthy and diseased human eye tissue
    Genomics. 2022 Mar;114(2):110286. doi: 10.1016/j.ygeno.2022.110286. Epub 2022 Feb 3. PMID: 35124170

    Wolf J, Boneva S, Rosmus DD, Agostini H, Schlunck G, Wieghofer P, Schlecht A, Lange C
    Deciphering the Molecular Signature of Human Hyalocytes in Relation to Other Innate Immune Cell Populations
    Invest Ophthalmol Vis Sci. 2022 Mar 2;63(3):9. doi: 10.1167/iovs.63.3.9. PMID: 35266958

    Wolf J, Boneva S, Rosmus DD, Agostini H, Schlunck G, Wieghofer P, Schlecht A, Lange C
    In-Depth Molecular Profiling Specifies Human Retinal Microglia Identity
    Front Immunol. 2022 Mar 18;13:863158. doi: 10.3389/fimmu.2022.863158. eCollection 2022. PMID: 35371110

    Wolf J, Hajdu RI, Boneva S, Schlecht A, Lapp T, Wacker K, Agostini H, Reinhard T, Auw-Hädrich C, Schlunck G, Lange C
    Characterization of the Cellular Microenvironment and Novel Specific Biomarkers in Pterygia Using RNA Sequencing
    Front Med (Lausanne). 2022 Jan 31;8:714458. doi: 10.3389/fmed.2021.714458. eCollection 2021. PMID: 35174178

    Behera A, Jain P, Ganguli G, Biswas M, Pattanaik KP, Nayak B, Ergün S, Hagens K, Redinger N, Saqib M, Mishra BB, Schaible UE, Karnati S, Sonawane A
    Mycobacterium tuberculosis Acetyltransferase Suppresses Oxidative Stress by Inducing Peroxisome Formation in Macrophages
    Int. J. Mol. Sci. 2022, 23(5), 2584; https://doi.org/10.3390/ijms23052584

    Wolf J, Schlecht A, Rosmus DD, Boneva S, Agostini H, Schlunck G, Wieghofer P, Lange C
    Comparative transcriptome analysis of human and murine choroidal neovascularization identifies fibroblast growth factor inducible-14 as phylogenetically conserved mediator of neovascular age-related macular degeneration
    Biochim Biophys Acta Mol Basis Dis. 2022 Apr 1;1868(4):166340. doi: 10.1016/j.bbadis.2022.166340. Epub 2022 Jan 12. PMID: 35032596