Deutsch Intern
    Institut für Anatomie und Zellbiologie

    Publikationen 2021

    Schlecht A, Thien A, Wolf J, Prinz G, Agostini H, Schlunck G, Wieghofer P, Boneva S, Lange C
    Immunosenescence in Choroidal Neovascularization (CNV)-Transcriptional Profiling of Naïve and CNV-Associated Retinal Myeloid Cells during Aging
    Int J Mol Sci. 2021 Dec 10;22(24):13318. doi: 10.3390/ijms222413318. PMID: 34948115

    Boneva SK, Wolf J, Hajdú RI, Prinz G, Salié H, Schlecht A, Killmer S, Laich Y, Faatz H, Lommatzsch A, Busch M, Bucher F, Stahl A, Böhringer D, Bengsch B, Schlunck G, Agostini H, Lange CAK
    In-Depth Molecular Characterization of Neovascular Membranes Suggests a Role for Hyalocyte-to-Myofibroblast Transdifferentiation in Proliferative Diabetic Retinopathy
    Front Immunol. 2021 Nov 2;12:757607. doi: 10.3389/fimmu.2021.757607. eCollection 2021. PMID: 34795670

    Zhang J, Cai J, Cui Y, Jiang S, Wei J, Kim YC, Chan J, Thalakola A, Le T, Xu L, Wang L, Jiang K, Wang X, Wang H, Cheng F, Buggs J, Koepsell H, Vallon V, Liu R
    Role of the macula densa sodium glucose cotransporter type 1-nitric oxide synthase 1-tubuloglomerular feedback pathway in diabetic hyperfiltration
    Kidney Int. 2021 Nov 26:S0085-2538(21)01078-4. doi: 10.1016/j.kint.2021.10.037. Online ahead of print. PMID: 34843754

    Rani A, Jakhmola Sh  , Karnati S, Parmar HS,  Jha HC
    Potential entry receptors for human γ-herpesvirus into epithelial cells: a plausible therapeutic target for viral infections
    PMID: 34800753 , DOI: 10.1016/j.tvr.2021.200227

    Watermann C, Meyer MT, Valerius KP, Kleefeldt F, Wagner S, Wittekindt C, Klussmann JP, Ergün S, Baumgart-Vogt E, Karnati S
    Peroxisomes in the mouse parotid glands: An in-depth morphological and molecular analysis
    Ann Anat. 2021 Nov;238:151778. doi: 10.1016/j.aanat.2021.151778. Epub 2021 Jun 4. PMID: 34091056

    Luetkens KS, Ergün S, Huflage H, Kunz AS, Gietzen CH, Conrads N, Pennig L, Goertz L, Bley TA, Gassenmaier T, Grunz JP
    Dose reduction potential in cone-beam CT imaging of upper extremity joints with a twin robotic x-ray system
    Sci Rep. 2021 Oct 11;11(1):20176. doi: 10.1038/s41598-021-99748-1. PMID: 34635787

    Grunz JP, Weng AM, Gietzen CH, Veyhl-Wichmann M, Pennig L, Kunz A, Schmitt R, Ergün S, Bley TA, Gassenmaier T
    Evaluation of Ultra-High-Resolution Cone-Beam CT Prototype of Twin Robotic Radiography System for Cadaveric Wrist Imaging
    Acad Radiol. 2021 Oct;28(10):e314-e322. doi: 10.1016/j.acra.2020.06.018. Epub 2020 Jul 10. PMID: 32654956

    Schlecht A, Vallon M, Wagner N, Ergün S, Braunger BM
    TGFβ-Neurotrophin Interactions in Heart, Retina, and Brain
    Biomolecules. 2021 Sep 14;11(9):1360. doi: 10.3390/biom11091360. PMID: 34572573

    Zhang P, Schlecht A, Wolf J, Boneva S, Laich Y, Koch J, Ludwig F, Boeck M, Thien A, Härdtner C, Kierdorf K, Agostini H, Schlunck G, Prinz M, Hilgendorf I, Wieghofer P, Lange C
    The role of interferon regulatory factor 8 for retinal tissue homeostasis and development of choroidal neovascularisation
    J Neuroinflammation. 2021 Sep 20;18(1):215. doi: 10.1186/s12974-021-02230-y. PMID: 34544421

    Schlecht A, Boneva S, Salie H, Killmer S, Wolf J, Hajdu RI, Auw-Haedrich C, Agostini H, Reinhard T, Schlunck G, Bengsch B, Lange CA
    Imaging mass cytometry for high-dimensional tissue profiling in the eye
    BMC Ophthalmol. 2021 Sep 20;21(1):338. doi: 10.1186/s12886-021-02099-8. PMID: 34544377

    Dogan L, Scheuring RG, Wagner N, Ueda Y, Schmidt S, Wörsdörfer P, Groll J, Ergün S
    Human iPSC-derived mesodermal progenitor cells preserve their vasculogenesis potential after extrusion and form hierarchically organized blood vessels
    Biofabrication. 2021 Sep 14. doi: 10.1088/1758-5090/ac26ac. Online ahead of print. PMID: 34521078

    Rajendran R, Rajendran V, Giraldo-Velasquez M, Megalofonou FF, Gurski F, Stadelmann C, Karnati S, Berghoff M
    Oligodendrocyte-Specific Deletion of FGFR1 Reduces Cerebellar Inflammation and Neurodegeneration in MOG 35-55-Induced EAE
    Int J Mol Sci. 2021 Aug 31;22(17):9495. doi: 10.3390/ijms22179495. PMID: 34502405

    Upcin B, Henke E, Kleefeldt F, Hoffmann H, Rosenwald A, Irmak-Sav S, Aktas HB, Rückschloß U, Ergün S
    Contribution of Adventitia-Derived Stem and Progenitor Cells to New Vessel Formation in Tumors
    Cells. 2021 Jul 7;10(7):1719. doi: 10.3390/cells10071719. PMID: 34359889

    Qin Z, Liu F, Blair R, Wang C, Yang H, Mudd J, Currey JM, Iwanaga N, He J, Mi R, Han K, Midkiff CC, Alam MA, Aktas BH, Heide RSV, Veazey R, Piedimonte G, Maness NJ, Ergün S, Mauvais-Jarvis F, Rappaport J, Kolls JK, Qin X
    Endothelial cell infection and dysfunction, immune activation in severe COVID-19
    Theranostics. 2021 Jul 6;11(16):8076-8091. doi: 10.7150/thno.61810. eCollection 2021. PMID: 34335981

    Meyer MT, Christoph Watermann C, Dreyer T, Wagner S, Wittekindt C, Klussmann JP, Ergün S, Baumgart-Vogt E, Karnati S
    Differential Expression of Peroxisomal Proteins in Distinct Types of Parotid Gland Tumors
    Int. J. Mol. Sci. 2021, 22(15), 7872; https://doi.org/10.3390/ijms22157872  Published: 23 July 2021

    Liu F, Han K, Blair R, Kenst K, Qin Z, Upcin B, Wörsdörfer P, Midkiff CC, Mudd J, Belyaeva E, Milligan NS, Rorison TD, Wagner N, Bodem J, Dölken L, Aktas BH, Vander Heide RS, Yin XM, Kolls JK, Roy CJ, Rappaport J, Ergün S, Qin X
    SARS-CoV-2 Infects Endothelial Cells In Vivo and In Vitro
    Front Cell Infect Microbiol. 2021 Jul 6;11:701278. doi: 10.3389/fcimb.2021.701278. eCollection 2021. PMID: 34307198

    Bielmeier CB, Roth S, Schmitt SI, Boneva SK, Schlecht A, Vallon M, Tamm ER, Ergün S, Neueder A, Braunger BM
    Transcriptional Profiling Identifies Upregulation of Neuroprotective Pathways in Retinitis Pigmentosa
    Int J Mol Sci. 2021 Jun 11;22(12):6307. doi: 10.3390/ijms22126307. PMID: 34208383

    Jordan MC, Jäckle V, Scheidt S, Gilbert F, Hölscher-Doht S, Ergün S, Meffert RH, Heintel TM
    Trans-obturator cable fixation of open book pelvic injuries
    Sci Rep. 2021 Jun 29;11(1):13463. doi: 10.1038/s41598-021-92755-2. PMID: 34188088

    Gartiwa G, Damia U, Megawati EI Pradipta S, Gunawan G, Karnati S, Wihadmadyatami H, Kusindarta DL
    Morphological characterization of Horsfield’s treeshrew Tupaia javanica lingual papillae: Light microscopy and scanning electron microscopy studies
    Anat Histol Embryol. 2021 Jun 29. doi: 10.1111/ahe.12724. Online ahead of print. PMID: 34184774

    Meyer MT, Watermann C, Dreyer T, Ergün S, Karnati S
    2021 Update on Diagnostic Markers and Translocation in Salivary Gland Tumors
    Int J Mol Sci. 2021 Jun 24;22(13):6771. doi: 10.3390/ijms22136771. PMID: 34202474

    Rajendran R, Böttiger G, Dentzien N, Rajendran V, Sharifi B, Ergün S, Stadelmann C, Karnati S, Berghoff M
    Effects of FGFR Tyrosine Kinase Inhibition in OLN-93 Oligodendrocytes
    Cells. 2021 May 25;10(6):1318. doi: 10.3390/cells10061318. PMID: 34070622

    Horder H, Guaza Lasheras M, Grummel N, Nadernezhad A, Herbig J, Ergün S, Teßmar J, Groll J, Fabry B, Bauer-Kreisel P, Blunk T
    Bioprinting and Differentiation of Adipose-Derived Stromal Cell Spheroids for a 3D Breast Cancer-Adipose Tissue Model
    Cells. 2021 Apr 3;10(4):803. doi: 10.3390/cells10040803. PMID: 33916870

    Karnati S, Seimetz M, Kleefeldt F, Sonawane A, Madhusudhan T, Bachhuka A, Kosanovic D, Weissmann N, Krüger K and Ergün S
    Chronic Obstructive Pulmonary Disease and the Cardiovascular System: Vascular Repair and Regeneration as a Therapeutic Target
    Front. Cardiovasc. Med., 12 April 2021 | https://doi.org/10.3389/fcvm.2021.649512

    Rajendran R, Böttiger G, Stadelmann C, Karnati S and Berghoff M
    FGF/FGFR Pathways in Multiple Sclerosis and in Its Disease Models
    Cells. 2021 Apr; 10(4): 884.Published online 2021 Apr 13. doi: 10.3390/cells10040884

    Koepsell H
    Update on drug-drug interaction at organic cation transporters: mechanisms, clinical impact, and proposal for advanced in vitro testing
    Expert Opin Drug Metab Toxicol. 2021 Apr 26. doi: 10.1080/17425255.2021.1915284. Online ahead of print. PMID: 33896325

    Grunz JP, Huflage H, Heidenreich JF, Ergün S, Petersilka M, Allmendinger T, Bley TA, Petritsch B
    Image Quality Assessment for Clinical Cadmium Telluride-Based Photon-Counting Computed Tomography Detector in Cadaveric Wrist Imaging
    Invest Radiol. 2021 Apr 20. doi: 10.1097/RLI.0000000000000789. Online ahead of print. PMID: 33882030

    Tjahjono Y, Karnati S, Foe K, Anggara E, Gunawan YN, Wijaya H, Steven, Suyono H, Esar SY, Hadinugroho W, Wihadmadyatami H, Ergün S, Widharna RM, Caroline
    Anti-inflammatory activity of 2-((3-(chloromethyl)benzoyl)oxy)benzoic acid in LPS-induced rat model
    Prostaglandins Other Lipid Mediat. 2021 Apr 5:106549. doi: 10.1016/j.prostaglandins.2021.106549. Online ahead of print. PMID: 33831580

    Wagner N, Mott K, Upcin B, Stegner D, Schulze H, Ergün S
    CXCL12-Abundant Reticular (CAR) Cells Direct Megakaryocyte Protrusions across the Bone Marrow Sinusoid Wall
    Cells. 2021 Mar 24;10(4):722. doi: 10.3390/cells10040722. PMID: 33804965

    Kamali S, Rajendran R, Stadelmann C, Karnati S, Rajendran V, Giraldo-Velasquez M, Berghoff M
    Oligodendrocyte-specific deletion of FGFR2 ameliorates MOG 35-55 -induced EAE through ERK and Akt signalling
    Brain Pathol. 2021 Mar;31(2):297-311. doi: 10.1111/bpa.12916. Epub 2021 Jan 4. PMID: 33103299

    Koepsell H.
    General Overview of Organic Cation Transporters in Brain
    Handb Exp Pharmacol. 2021 Mar 30. doi: 10.1007/164_2021_449.

    Janz A, Zink M, Cirnu A, Hartleb A, Albrecht C, Rost S, Klopocki E, Günther K, Edenhofer F, Ergün S, Gerull B
    CRISPR/Cas9-edited PKP2 knock-out (JMUi001-A-2) and DSG2 knock-out (JMUi001-A-3) iPSC lines as an isogenic human model system for arrhythmogenic cardiomyopathy (ACM)
    Stem Cell Res. 2021 Feb 18;53:102256.doi: 10.1016/j.scr.2021.102256

    Koeniger T, Bell L , Mifka AEnders M Hautmann V , Mekala SR , Kirchner P Ekici A , Schulz C , Wörsdörfer P Mencl S , Kleinschnitz C , Ergün S , Kuerten S  
    Bone marrow-derived myeloid progenitors in the leptomeninges of adult mice
    Stem Cells. 2021 Feb;39(2):227-239.doi: 10.1002/stem.3311

    Ferté L , Marino A, Battault S, Bultot L, Van Steenbergen A, Bol A, Cumps J, Ginion A, Koepsell H, Dumoutier L, Hue L,  Horman S,  Bertrand L, Beauloye CNew insight in understanding the contribution of SGLT1 in cardiac glucose uptake: evidence for a truncated form in mice and humans
    Am J Physiol Heart Circ Physiol. 2021 Jan 8.doi: 10.1152/ajpheart.00736.2019.

    Mataram MBA ,Hening P,  Harjanti F , Karnati S, Wasityastuti W,  Nugrahaningsih DAA , Kusindarta DL  , Wihadmadyatami HThe neuroprotective effect of ethanolic extract Ocimum sanctum Linn. in the regulation of neuronal density in hippocampus areas as a central autobiography memory on the rat model of Alzheimer's disease
    J Chem Neuroanat. 2021 Jan;111:101885.doi: 10.1016/j.jchemneu.2020.101885.